Yes, intentionally and unintentionally. Unintentionally, I was playing a pickup game of basketball in university. I had the ball and cross-cover dribbled the guy guarding me. I got past him, but my elbow connected to his temple/eye area and he was knocked out. He had a black eye for 3 weeks. Intentional: Also in university, I was clubbing with a close friend. A guy got aggressive and hit on her and started grabbing/pushing her. I got in the way. We shoved each other, and I clocked him on the chin. Never seen him again.
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TPBM would like to experience what Michael Douglas did in the "game". Basically, an elaborate prank that makes it seem like your world is turned upside down.