You're at the point where marriage counseling would be a good next step. A good marriage counselor can help resolve differences when simply talking isn't leading anywhere. If your wife is suffering from depression, then they can navigate a solution to that issue as well. Your wife will also have to take the issue more seriously when you insist on getting professional help. I wouldn't wait too long. The longer this goes on, the further you will drift apart and the harder it will be to rebuild the relationship. Now that you still feel the need to be with her, it's a good time to fix things. Good luck!
“This planet has - or rather had - a problem, which was this: most of the people living on it were unhappy for pretty much of the time. Many solutions were suggested for this problem, but most of these were largely concerned with the movement of small green pieces of paper, which was odd because on the whole it wasn't the small green pieces of paper that were unhappy.” ― Douglas Adams, The Hitchhiker's Guide to the Galaxy